Roaccutane / Accutane
(Reader Contribution to
10 Worst Prescription Drug Side Effects)

This medication is downright scary, when I was a teen this was new and the doctor gave me a brochure for this. I don't know if they are still in the warning list but I remember them cautioning about, losing the palms and soles of your feet and rectal bleeding, along with the Biggie "DO NOT GET PREGNANT" as it is a teratogen (apparently it turns the fetus to Silly Putty)
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10 Worst Prescription Drug Side Effects